Other GI motility agents may have conflicting mechanisms
For how things stand across the Atlantic, see our explainer on whether peptides are legal in the UK
These medicationsincluding semaglutide (injectable Ozempic, oral Rybelsus, injectable Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda)mimic the action of endogenous GLP-1 while resisting degradation by the enzyme dipeptidyl peptidase-4 (DPP-4)
Diabetologia, 66(10), 2311-2323
Early Phase 2 trial data have generated significant clinical interest, but retatrutide has not yet received MHRA or EMA authorisation and remains confined to research settings
* Draw out all of the mixed solution from both vials with the syringe and place into your nasal bottle (gently) You now have 10 days worth of mix to use twice a day