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Furin-mediated priming of viral S protein at S1/S2 (P R RA R 685 ) [the underlined AAs refer to critical residues needed for the furin recognition] is a key determinant in the pathogenesis of COVID-19 55,73,329

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Standard subcutaneous injection technique applies: pinch a fold of skin, insert the needle at 45-90 degrees, inject slowly, withdraw and apply gentle pressure

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H., Hofman, P