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The authors of this study showed that Zn supplementation produced MT overexpression in the heart, resulting in the prevention of diabetes-triggered ATP synthase nitration, inactivation, inflammation, and profibrotic response

Contacts Raymond MacDougall NIH/NHGRI 301-402-0911 [email protected] Anne Oplinger NIH/NIAID 301-402-1663 [email protected] Eric Jome Illinois State University 309-438-5631 [email protected] Last updated: May 15, 2012

[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Novak Kujundi R., Stepani V., Milkovi L., ipak Gaparovi A., Tomljanovi M., Gall Troelj K

1 Even in darkness, the retina consumes large amounts of oxygen-often more than it does in light-making it particularly vulnerable to oxidative damage

In addition, reactive astrocytes at the perimeter of the fibrotic scar proliferate to form perilesional barrier that protects the adjacent viable nervous tissue