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[6] [42] [43] For single doses of lipophilic, multi-compartment drugs, clinical duration after onset is often driven by the distribution () phase, because by the time distribution equilibrium is reached plasma levels are frequently below any minimal effective concentration, so the terminal phase has little bearing on observable effects

[DOI] [PMC free article] [PubMed] [Google Scholar] 232.Blondin DP, Labb SM, Phoenix S, Gurin B, Turcotte E, Richard D, et al

Lethal neonatal deficiency of carnitine palmitoyltransferase II associated with dysgenesis of the brain and kidneys

Patients may also become upset if there is any deviation from their eating plan, according to Ihlenfeld

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