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MG Traber, JF Vitamins C and E: beneficial effects from a mechanistic perspective
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Among these, Claudin-5, Occludin, and zonula occludens-1 (ZO-1) are central to maintaining the structural integrity and function of tight junctions (61).Claudin-5, a principal protein in inter-endothelial tight junctions, determines BBB selective permeabilitys (62)
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Treatment with 5-Amino-1MQ combined with diet transition produced dramatic whole-body adiposity and weight loss, rapidly normalising these measures to levels comparable to age-matched lean control animals an outcome that diet switch alone was unable to achieve in the same time frame
From 2007 to 2011, approximately 84% of military-related TBIs were classified as mTBIs (Mondello et al., 2014)
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