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doi: 10.1677/joe.0.1740233 [DOI] [PubMed] [Google Scholar] 117
Tirzepatide (dual hormone action) may lead to slightly higher weight loss, while Semaglutide (single hormone) has a longer track record and multiple dosing options
GLP-1 effects on the brain The GLP-1 receptor is expressed in the hypothalamus, brainstem, and other parts of the central nervous system, helping GLP-1 drugs to reduce body weight by decreasing hunger and increasing feelings of satiety
McBeth, M.D
Exendin-4 protected against cognitive dysfunction in hyperglycemic mice receiving an intrahippocampal lipopolysaccharide injection
Patients seeking GLP-1-based therapy should consult healthcare providers about FDA-approved options rather than relying on unproven supplements
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