Seek urgent medical attention if you experience: Severe abdominal pain , particularly if accompanied by vomiting, fever or jaundice (yellowing of skin/eyes), as this could indicate pancreatitis or gallbladder problemsrare but serious adverse effects requiring immediate assessment Persistent vomiting that prevents adequate fluid intake, which may lead to dehydration and potential kidney problems Severe hypoglycaemia (low blood sugar) with symptoms such as confusion, loss of consciousness or inability to treat yourself For severe symptoms, contact NHS 111, attend A&E, or call 999 if you are severely unwell
The chemoreceptor trigger zone in your brainan area sensitive to GLP-1 activityalso contributes to nausea sensation in the first few weeks of therapy
Blood sugars increase As mentioned earlier, semaglutide also functions as a blood sugar moderator
Rizzo M, Abate N, Chandalia M, Rizvi AA, Giglio RV, Nikolic D, et al
doi: 10.1016/j.phrs.2018.09.025 7 SumidaYYonedaM
Women with a history of gallbladder issues or pancreatitis should discuss these risks specifically with their doctor before starting GLP-1 therapy
