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This pathway was also investigated in RAW264.7 cells, where IFN- production, accompanied by STAT-1 phosphorylation, was detected 6 hours after LPS exposure

2 min each), and stained with cresyl violet acetate solution (Solarbio, at 60C for 30 min in light-protected conditions)

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Therefore, Erastin ultimately decreases the amount of GSH

The transferrin receptor (TfR) functions as the primary receptor for cellular iron uptake, binding to iron-containing ligands to form Tf-Fe complexes, thereby initiating the process of iron uptake [15]