Clinical eligibility is defined by a diagnosis of obesity, diabetes or overweight with other present risk factors
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While constipation itself does not cause fever, the combination suggests something beyond simple slow transit that needs investigation
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Interestingly, higher incidence of diabetic retinopathy (DR) complications was noted in patients taking semaglutide (3.0%) compared to placebo (1.5%) in clinical trials, with greater risk in those with a history of DR [32]