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You should contact your GP if: Your B12 level is significantly elevated (markedly above your local laboratory's reference range) without obvious explanation such as supplementation You have persistent elevation on repeat testing You experience unexplained symptoms such as unintentional weight loss, persistent fatigue, night sweats, fever, or abdominal discomfort You notice unusual bruising, bleeding, or enlarged lymph nodes You have jaundice (yellowing of skin or eyes) or other signs of liver disease You have a history of liver disease, kidney disease, or blood disorders Immediate medical attention (contact NHS 111 or attend A&E) is warranted if you experience severe symptoms such as significant bleeding, severe abdominal pain, confusion, or signs of acute illness, though these would rarely be directly related to elevated B12 itself

(Tells cells to absorb more glucose from the bloodstream and helps convert glucose into energy that can be used by muscles.) A GLP-1 like Ozempic and Wegovy

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Disruption of the folding could cause the protein to lose its normal function or to become unstable

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