Females with ME/CFS and Long COVID exhibited significantly higher total ROS levels that correlated with the hyperproliferation of T-cells, while males presented with pronounced mitochondrial lipid oxidative damage
So for some people that looks like cardio, but its always important to have at least some resistance or strength training while youre taking these medications to help preserve your muscle mass
The study recruited 411 patients and showed that danuglipron reduced glycated hemoglobin, fasting blood glucose and body weight at week 16 compared with placebo and was well tolerated without the need for injections or fasting restrictions (Saxena et al., 2023)
Table 1 summarizes the dose adjustment of human doses
Orforglipron also reportedly has a simpler production process than injected GLP-1 drugs such as Ozempic and tirzepatide (sold as Mounjaro) and does not require cold storage factors that could help improve access to the drug if it is approved for use
Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons
