Importantly, the genetic and pharmacological inhibition of MT-1G enhances the anticancer activity of sorafenib in vitro and tumor xenograft models (Sun et al., 2016a)
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Reddit's share of responses where it's the only cited source increased 31% from October 2025 to January 2026, which indicates a bigger story
Tumor characteristics included lesion size, level of bony laminectomy, nerve versus intradural involvement, and laterality (in the midline, right, or left)
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The practical consequence is clear regardless of the mechanistic explanation: robust GH secretion without the hormonal background noise that complicates interpretation