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However, the triagonist failed to enhance insulin secretion in islets lacking both Glp-1r and Gipr and upon treatment with the GLP-1 receptor-specific antagonist exendin-3 (939)

Grounds MD, Radley HG, Gebski BL, Bogoyevitch MA, Shavlakadze T

DOI : 10.3389/fphar.2025.1702448

Ketamine administration reduces amygdalo-hippocampal reactivity to emotional stimulation

Gastrointestinal side effects are the primary clinical concern: nausea (44%), diarrhea (30%), vomiting (24%), and constipation (24%) are common, particularly during dose escalation

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