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After reviewing clinical trial data, post-marketing surveillance reports, and real-world evidence across millions of prescriptions, the EMA concluded in 2024 that the available evidence does not support a causal association between GLP1 receptor agonists and suicidal or self-injurious behavior

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If you notice diminished appetite suppression, slower weight loss progression, or decreased satiety compared to earlier weeks on the same dose, temperature fluctuations or light exposure may have weakened your medication