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Clinical dilemmas of MDR in refractory tumors The clinical management of MDR in refractory cancersincluding pancreatic cancer, glioblastoma, triple-negative breast cancer (TNBC), and platinum-resistant ovarian cancer (see Table 1)remains a formidable and largely unmet challenge, as both conventional and emerging therapeutic strategies frequently encounter failure

These cells are not only deprived of catalase but also have a higher concentration of mitochondria [80] which is one of the major sources of superoxide and hydrogen peroxide in the cell through the electron transport pathway

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Shikonin attenuates acetaminophen-induced acute liver injury via inhibition of oxidative stress and inflammation

As you can see, there can be considerable variation in the treatment plan for Clarithromycin and Azithromycin despite both of them being the same type of antibiotic

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