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Thus, we next designed and synthesized a set of eight compounds that contain an aromatic aldehyde in place of the aliphatic amine of UNC8732, with the expectation that these aromatic aldehydes would be more stable in a cellular environment and would be easier to synthesize than their aliphatic counterparts, while potentially maintaining the ability to engage C326 in a similar reversible covalent fashion

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This powerful antioxidant effectively protects against oxidation and has a half-life that is 5-8 times greater in the blood compared to conventional Glutathione supplements

While technically possible, we dont recommend it as it increases the risk of contamination with each step

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This specific conformation of c-MET dimer is able to bring the two KDs into close proximity for trans -autophosphorylation