I recommended against trying compounded semaglutide
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That is why "does this drug help with edema" is not a question a label can answer generically
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N Engl J Med 375:18341844 McMurray JJV, Solomon SD, Inzucchi SE, Kber L, Kosiborod MN, Martinez FA, DAPA-HF Trial Committees and Investigators et al (2019) Dapagliflozin in patients with heart failure and reduced ejection fraction
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