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A Phase 2 trial (NCT01311518) was designed to test RGN-352 in ~75 heart attack patients, but was placed on FDA clinical hold in 2011 due to manufacturing (GMP) compliance issues at the contract site not safety concerns with the drug itself

This activates protein kinase A, which then activates hormone-sensitive lipase, the enzyme responsible for breaking down stored triglycerides into free fatty acids that can be burned for energy

Meta-analysis: Helicobacter pylori 'test and treat' compared with empirical acid suppression for managing dyspepsia

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This ratio maps a 250 mcg dose to 10 units on a U-100 syringe

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