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[11] The hypothesis underlying microdosing is that lower doses might provide some metabolic benefit whilst minimising these troublesome symptoms, potentially improving treatment adherence
metformin on endothelial function in obese patients with pre-diabetes: a randomized trial
Hormone and Metabolic Research , 36(1112), 735741
If reflux is an issue, you may want to limit coffee or switch to lower-acid options
More importantly, an orthostatic vitals test may confirm a suspected dysautonomia without the use of expensive diagnostic testing
It is the difference between managed transition and metabolic chaos
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