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however, there were important limitations to consider, including small sample sizes, a lack of long-term observation, the use of a single species or strain, the lack of in-depth exploration of cellular or molecular mechanisms, failure to assess other aspects of reproductive function, a lack of validation of the clinical relevance, and a failure to consider individual differences in drug dosages

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Males had more neural stem cells than females, whereas females showed a regional difference with more neural stem cells in the ventral, compared with dorsal, DG In the present study, males had a greater density of Sox2-ir cells in the dorsal DG compared with females