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doi: 10.3389/fneur.2025.1643305 Received 08 June 2025 Accepted 20 August 2025 Published 22 September 2025 Volume 16 - 2025 Edited by Marcelo Mendona, Champalimaud Foundation, Portugal Reviewed by Ins Figueira, NOVA University of Lisbon, Portugal Alina Sacarescu, Grigore T