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Yes, semaglutide demonstrates consistent safety and efficacy in men across clinical trials and real-world use

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Eli Lilly announced positive topline Phase 3 results in March 2026 for a type 2 diabetes study, and multiple Phase 3 trials remain active across obesity and related conditions

Cancer Risk Elevated levels of insulin-like growth factor-1 (IGF-1), which is the downstream effect of GH activity, have also raised theoretical concerns about an increased risk of cancer: According to Roberts, IGF-1 promotes cellular proliferation and inhibits apoptosis, two mechanisms that may contribute to the development of cancer cells in predisposed individuals (22)