If you are on 4mg and wondering whether it is "working," the answer is: it depends when you started that dose
Water alone just doesnt cut it
Calorie restriction appears to affect neurobiological pathways that control appetite, hunger, cravings and body weight, such that there is increased food intake and weight gain (Brown et al, 2022)
I have many, many patients who live in a state of mild to moderate dehydration, because they dont feel the need to drink, so I end up saying, OK, drink a full glass of water with every meal, and ideally two or more, she said
If considering a probiotic supplement, discuss with your healthcare provider first, particularly if you have a compromised immune system
Sorry, not sorry for the pun, but this should NOT be one size fits all, and the objective of #obesitydrugdevelopment should NOT merely be the most weight loss as fast as possible for everyone and the same dose for both wt loss and wt maintenance