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Quantification of these axonal elements were only considered to be in close apposition onto a target neuron in the PVH if they were touching by voxel-to-voxel contact, with no unlabeled voxels between the presynaptic and postsynaptic elements of the presumptive synapse

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Patients are encouraged to report any suspected adverse reactions to medicines via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or the Yellow Card app)