It helps prevent oxidative stress in cells and protects them from free radicals that potentially damage DNA and RNA
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Immune functions of pattern recognition receptors in Lepidoptera
The ubiquitin homologue, Bacteroides fragili s ubiquitin (BfUbb), secreted by some strains of the gut bacterium Bacteroides fragilis , is another example of a gut-derived component that may enter systemic circulation following a breach of the intestinal barrier and contribute to the pathogenesis of SLE (Patrick et al
PMID 29600692
For example, animal studies have shown that GLP-1 receptor agonists can reduce pain signaling, including the activity of calcitonin gene-related peptide, and lower neuroinflammation both of which are key players in the development of migraine