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Nevertheless, empagliflozin consistently slowed eGFR decline compared with placebo across all subgroups [48]

This article breaks down why semaglutide cannot currently be delivered through skin, what the MHRA says about such products, and how to choose safe, evidence-based obesity treatments in the UK

Patients in the UK seeking weight management support should consult their GP or an NHS specialist obesity service, where NICE-recommended options such as semaglutide (Wegovy) and tirzepatide (Zepbound) are currently available

We will update this article as trial results come in throughout 2026

Delayed gastric emptying can be addressed with a low-fat diet, frequent small meals, blood glucose monitoring, and agents that increase gastric motility