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however, those studies are very few

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Supplementary information Supplementary Tables 14 and Note

An initial inspection of the TIN2 TBM site showed that the closest neighbouring TRF1 TRFH molecule in this new crystal was further away than in the previous crystal system, this time exposing both the TIN2 leucine and phenylalanine binding pockets to the solvent (Fig

This can lead to an "osmotic effect," where the supplement draws water into the colon, resulting in loose stools or diarrhea

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