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The temptation to escalate the dose because nothing is happening yet is exactly the mistake the timeline section is designed to head off the mechanism is cumulative, not dose-chased

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In the United Kingdom, vitamin B12 deficiency is relatively common, with prevalence varying depending on the population studied and the biochemical threshold used for diagnosis

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A 2025 University of Michigan study found states with largest Medicaid reductions saw: Higher rates of buprenorphine treatment discontinuation Increased cash payments for addiction medications Greater overdose risks from interrupted MAT access This proved particularly concerning since only 5% of Indiana Medicaid enrollees with opioid use disorder received treatment prior to unwinding