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The primary mechanism involves copper delivery to dermal tissues where this essential cofactor supports numerous enzymatic processes including collagen synthesis, elastin production, glycosaminoglycan formation, and antioxidant enzyme activation

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Oral supplements may cause mild digestive discomfort in some individuals, while injectable forms may involve risks such as local irritation at the injection site or allergic reactions in certain cases

A particular strength of this study was the inclusion of individuals with type 2 diabetes in both parts of the study, allowing efficient conclusions on the potential clinical utility of MEDI4166 in the target population to be made