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This 48-week, phase 2, dose-ranging trial enrolled 338 adults with obesity (BMI 30) but without diabetes, randomising participants to placebo or one of four retatrutide doses: 1mg, 4mg, 8mg, or 12mg administered subcutaneously once weekly

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Why Researchers Study the Amylin Pathway Interest in the amylin pathway has increased because it represents a biological system distinct from several other metabolic signaling pathways currently under investigation

Gruber, C