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A similar change was reported in diethylnitrosamine treated mice as part of a basophilic focus of cellular alteration response (Goldfarb et al

(3) development of next-generation GLP-1 receptor-targeted therapeutics with enhanced specificity and reduced off-target effects [129,130,131,132]

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Sitagliptin, a DPP-4 inhibitor, showed a decrease in liver triglyceride content, expression of lipogenesis genes and gluconeogenesis in wild type mice [24]