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But for people who hate needles, these medications hold a glaring, obvious drawback: They require taking a weekly shot

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From those bespoke circles of Silicon Valley health nuts, their inclusion on the notoriously cheap ecommerce site Temu best known for labor issues and selling dirt-cheap goods, like electronics that catch fire signals that the little vials are hitting the mainstream in a major, and potentially disastrous, way

These cells detect the presence of nutrients in the intestinal lumen via chemosensory G protein-coupled receptors (GPCRs) and taste receptors , and in response, release hormones that influence digestion , appetite , and glucose metabolism