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What happens to our sense of self when hunger can be turned off like a switch

GLP-1 receptor agonists typically reduce triglycerides by 10-20% in clinical studies

Providers are increasingly seeing side effects such as: Nausea, vomiting, and delayed gastric emptying Fatigue and muscle loss during rapid weight loss Micronutrient depletion from reduced food intake Emotional dysregulation related to appetite and blood sugar swings Plateaus or weight regain after discontinuation Some patients also feel disconnected from their hunger cues or experience anxiety about long-term dependency on injections

You should expect that your odds of losing a lot of weight (we are somewhat arbitrarily defining that as 10% or more of your body weight) are no better than 50/50

That's where I plan to stay

During the weight loss maintenance period, the fasting plasma glucose level decreased by further 0.2 mmol l 1 in the GLP-1RA group, in contrast to the control group where blood glucose concentrations increased by 0.3 mmol l 1 to the same level as before the weight loss even though the weight loss was maintained