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This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-amino-acid ligases (peptide synthases)
[DOI] [PubMed] [Google Scholar] 16.Ohkawa H., Ohishi N., Yagi K
Pickart, Journal Of Biomaterial Sciences Legal Status of GHK-Cu Peptide GHK-Cu is classified as a cosmetic ingredient when included in topical formulations such as serums, creams, and scalp solutions
Skin Rejuvenation and Anti-Aging Protocol Dose: 1 to 2 mg per day Route: Subcutaneous (abdomen, thigh, or upper arm) Frequency: Daily, 5 days on, 2 days off Cycle: 8 to 12 weeks on, 4 weeks off Expected results: 4 to 8 weeks for visible improvement Best for: Fine lines, skin elasticity, skin density, overall skin quality In a 12-week facial cream study (human trial, 71 women), 70% showed increased collagen production with GHK-Cu, compared to 50% with vitamin C and 40% with retinoic acid (Pickart et al., 2015)
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BPC-157 has been found to counteract side effects of NSAIDs, medications used in psychiatric conditions, and a number of heart medications
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