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placebo (0.97 vs 1.56 ml/min/1.73 m 2 per year, p 100 mg/g and consistently reduced UACR progression in patients with various degrees of albuminuria [23]

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[7] [12] However, Phase 2 trials are not powered to detect rare cardiovascular outcomes, and longer-term Phase 3 data including dedicated cardiovascular outcome trials will be essential to fully characterise the cardiac safety profile of retatrutide

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The Phase 3 TRIUMPH-4 data pushed that even higher, to 28.7% at 68 weeks