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The anionic nature of superoxide and the fact that it is mostly produced in the mitochondrial matrix determine that the bulk of antioxidant defenses to neutralize superoxide and other ROS reside in the matrix

117 End-processing enzymes, such as Artemis, trim DNA ends to prepare them for direct ligation

It plays a role in protecting cells from oxidative stress, recycling other antioxidants, and supporting normal liver detoxification pathways

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By affecting all of them, acarbose could potentially impact a myriad of metabolic and physiological processes [12]