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4 Gut microbiota-derived metabolites and depression Bacterial compounds found in the gut can enter the bloodstream affect brain regions and can interact with nearby gut components like hormonal cells or neurons, which can subsequently send signals to the brain (161)

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8 Conclusion Compelling scientific evidence now establishes that environmental endocrine disruptors pose profound threats to male reproductive health through complex molecular mechanisms involving hormonal disruption, oxidative stress induction, mitochondrial dysfunction, and epigenetic modifications

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