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Plasma and tissue GSH levels decline with age, while markers of oxidative damage increase, creating a "redox imbalance" implicated in the pathogenesis of age-related diseases [2][3][10][11]

J Clin Oncol (2019) 37:192734

[DOI] [PMC free article] [PubMed] [Google Scholar] 137.Westerterp-Plantenga MS, Lejeune MP, Kovacs EM

In addition, cellular experiments showed that SelP-H not only reduced intracellular ROS levels, but also reduced neurotoxicity induced by Cu/Cu-A 42 or Zn-A 42 complexes by 4060% [115, 116]

Start at 4 units (1 mg) for the first 15 days, then step up to 8 units (2 mg) at Day 16

2004 Jun;286(6):E916-26