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These can indicate cauda equina syndrome, a surgical emergency

As an example, the crystal violet or supravital blood stain of an infant with significant hyperbilirubinemia who was G6PD-deficient did not show the presence of Heinz bodies (Figure 2)

References Hathaway JT, Shah MP, Hathaway DB, Zekavat SM, Krasniqi D, Gittinger JW Jr et al