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Researchers should note that AOD 9604s pharmaceutical development was discontinued due to insufficient efficacy findings in clinical trials, which is relevant context when evaluating either compounds utility in a research setting.

Giorgi C, Marchi S, Pinton P

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Magnesium deficiency, in particular, is a well-established cause of muscle cramps and may go unrecognized in patients experiencing chronic gastrointestinal symptoms

The Nature Scientific Reports 2016 study confirmed that GHK-Cu produced no cytotoxicity to human keratinocytes at concentrations up to 5,800 micromolar over 72 hours and did not induce inflammatory biomarkers