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187189,191,192 In addition, Meriva mitigated inflammatory markers such as CRP, IL-1, IL-6, ESR, sCD40L, and sVCAM-1, WOMAC score, Karnofsky scale score, stiffness, negative effects on social function, and boosted physical performance capacity in osteoarthritis with excellent safety and tolerability (Figure 2)

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GHK-Cu is used in in vitro studies on fibroblast cultures (collagen, fibronectin synthesis), in tissue models (ECM remodeling) and in in vivo studies on animal models (angiogenesis and connective tissue remodeling processes)