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Yes, vitamin B12 deficiency is associated with recurrent mouth ulcers (aphthous stomatitis)
It has been studied in preclinical settings for its potential role in supporting tissue repair processes, inflammatory response balance, and cellular resilience
Some long-term patients develop or experience worsening GERD, especially if the stomach has stretched
For High Vitamin B12 Levels: Review supplement intake: Discontinue or adjust the dose if youre taking high-strength supplements
Even safety data on TB-500 (synthetic TB4) is relatively scarce, with only a few studies reporting the potential side effects of its systemic application: In a 2010 study in 10 participants, TB4 caused occasional mild to moderate symptoms like headache and dizziness but no serious reactions or toxicities, even at doses up to 1260mg, administered daily for up to two weeks
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