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In summary, accumulating evidence points to metabolism as a key determinant of meningococcal colonization and invasion, with important differences between hypervirulent and carrier strains ( Table 2 )

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Bioavailability refers to how much of a substance actually enters the circulation and is able to have an active effect

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2012;7:e45180

Removal of the N-terminal amino acids of chemokines significantly alters receptor selectivity