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In women with PCOS and obesity, metformin has been shown to improve insulin sensitivity, reduce insulin and androgen levels, and ameliorate menstrual cyclicity and ovulation rates 18,19,20

& Husain, M

Morgan Stanley estimates that ~9% of the U.S

However, tirzepatide seems to be at least as potent as GLP-1 RAs at lowering blood sugar in those with diabetes

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The safety, tolerability, pharmacokinetics and pharmacodynamics of an optimized dual GLP-1/GIP receptor agonist (BGM0504) in healthy volunteers: a dose-escalation phase I study