Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing sp1 glycosylation
N hot ng nh mt nam chm ht cc gc t do, kim loi nng v c t m c th hp th hng ngy qua thc phm, nc ung, khng kh v da, t kch thch c ch o thi v bo v c th khi tn thng
Surgical resection followed by adjuvant RT or concurrent chemoradiation (CRT) with salvage surgery acting as salvage therapyalso known as the organ preservation approachremains the cornerstone of treatment for locoregionally progressed HNSCC (68)
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