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While you could say that men have more lean muscle mass, and so theyre more apt to lose it, you also have to consider that because women have less, they have less to spare, says Dr

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4,5 The main hormones that regulate metabolic homeostasis are insulin and glucagon, which are secreted into circulation as required by islet-beta and alpha cells, respectively

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Overall, therefore, the main effects of GLP-1 are a reduction of fasting and postprandial blood glucose levels, lowering of body weight and protection from CVD, which are all therapeutic targets in type 2 diabetes (Fig