10 Thus, although our results suggest that GLP-1 secretion is not primarily regulated in a sleep-dependent manner in healthy men, the contribution of subtle changes in postprandial GLP-1 signaling to the deteriorating effect of sleep loss on glucose homeostasis and food intake regulation deserves a closer look in future investigations

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The primary limitations identified included the absence of a list of excluded studies and justification, as well as a written or registered protocol for the included studies, a lack of detailed funding sources, an assessment of risk of bias, and a discussion regarding the heterogeneity observed
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