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GR is expressed in virtually all tissues, with particularly high concentrations in metabolically active organs such as the liver, kidneys, and erythrocytes

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Furthermore, Caveolin-1 (encoded by the Cav1 gene), is differentially expressed between the intestinal and retinal Esm1 + populations by scRNA-seq (Supplementary Fig

Most of the studies have shown its therapeutic role in melasma, whereas some studies have contradicted this fact[] [Table 1]

Additionally, researchers have developed a range of glutathione-depleting nanodrugs for efficient cancer treatment [49], particularly in addressing chemotherapy resistance in TNBC [50]