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Stopping abruptly can cause nausea and rebound hunger
NADPH contributes to recycling in oxidized antioxidant systems involving glutathione, thioredoxins, glutaredoxins, and peroxiredoxins and maintains another reactive oxygen species (ROS)-detoxifying enzyme, catalase, in its active form, suggesting that the homeostatic level of G6PD-derived NADPH determines the rate of oxidative damage [8]
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In order to make GLP-1 better used in the clinic, drug developers modified its structure and developed a series of GLP-1R agonists (13)
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