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42 Interestingly, maxadilan, a peptidic PAC1R agonist, reorganized the ECD orientation and reshaped the ligand-binding pocket conformation, including ECL1 42 (Fig

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13 The patient had been taking olmesartan-hydrochlorothiazide before presentation

"This portfolio of publications, derived from three major trials, significantly advances our understanding of the wide-ranging benefits of GLP-1 agonists, while also highlighting key questions that remain," said JACC Editor-in-Chief Harlan Krumholz, MD, SM, FACC

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